During this time of COVID-19, organisations across Europe and the world are working hard to better understand the virus and how it impacts not only society as a whole but the more at-risk groups such as those living with chronic conditions. EBC invites everyone to please have a look through the various ongoing consultations as well as resources available for the brain community, listed below. If you have an ongoing survey or resource available, please don’t hesitate to contact us: firstname.lastname@example.org
EBC Members and Community
COVID-19 – Global Neuro Survey
The European Federation of Neurological Associations (EFNA) is disseminating the first global survey on disruption and mitigation strategies for restoring and maintaining services for children and adults with neurological disorders on behalf of the Neurology & COVID-19 Global Forum Working Group on Essential services. The survey aims to assess the extent to which services for children and adults with neurological disorders are being impacted by the COVID-19 pandemic and what measures have been put in place to mitigate these disruptions. You can find here an overview of the survey with Frequently Asked Questions (FAQs).
Survey on the impact of COVID-19 on neurology service delivery
Many surveys have captured the impact of the Covid-19 pandemic on patients’ access to treatment and care. With this survey, the European Federation of Neurological Associations (EFNA) in partnership with the European Academy of Neurology (EAN), want to better understand how care pathways were reconfigured for the neurology patient community during the first wave of the pandemic. However, more importantly, they want to capture recommendations to ensure that any future changes to service delivery are made in the interests of the patients – rather than, solely, in the interests of the healthcare system. This survey is open to anyone who is living with a neurological disorder and resides in Europe.
COVID-19 Survey for patients
We have all been affected by the current COVID-19 pandemic – and mental health has never been so much in the spotlight. This is an opportunity to underline the importance of mental health and to ensure appropriate understanding of the needs of patients, now as well as post-COVID. This is why GAMIAN-Europe has taken the initiative to carry out a survey, focusing on the patient experience and patient needs, both in the short as well as in the longer term.
Lean European Open Survey: studying SARS-CoV-2 collectively
The new SARS CoV II 2019 is spreading rapidly. Mandated by the ESCMID Emerging Infections Task Force (EITaF) and supported by the German Infectious Disease Society, the Lean European Open Survey (LEOSS) want to better understand the implications of the new virus on patients by systematically documenting patient data across Europe. Medical professionals are invited to register here.
EBC Members and Community
As the CoVID-19 pandemic spreads across Europe and the world, in response the European Academy of Neurology is launching EANcore CoVID-19. This resource aims to help neurologists in Europe and beyond prepare for and manage the challenges this global crisis is bringing. To support neurologists, EANcore CoVID-19 will provide up-to-date information on the pandemic, collate emerging data on neurological complications, publish reports from front-line doctors, the latest research, breaking news, and more, all to access in just one place.
COVID-19: Resource hub for neurology patients
The European Federation of Neurological Associations (EFNA) has created a page dedicated to disease specific information and other useful resources in relation to the coronavirus COVID-19 pandemic.
COVID-19 Resource centre
The page of the European Psychiatric Association (EPA) contains links to high-quality COVID-19 resources for both health professionals and the general public. The EPA will expand the selection to include resources in multiple languages as they become available.
GAMIAN-Europe: COVID-19 Platform
Global Alliance of Mental Illness Advocacy Networks-Europe (GAMIAN-Europe), a patient-driven pan-European organisation, has created a COVID-19 Platform where you can find international and national resources, COVID-19 helplines and services, input from their members and much more.
IBRO COVID-19 Series: Global Neuroscience Experiences
The COVID-19 pandemic has by now affected everyone, including the global neuroscience community. To capture the experiences of different brain researchers around the world, IBRO has launched its “COVID-19 Series: Global Neuroscience Experiences,” a collection of video interviews featuring personal perspectives from our community. We hope that this will serve as an inspiration and acknowledgement of the commitment and solidarity of scientists during such challenging times.
Autism Parenting Magazine: COVID-19 and Autism
Autism Parenting Magazine, the leading magazine for parents of autistic children as well as professionals seeking to work with children on the spectrum, has published essential resources to support parents of autistic children during the COVID-19 pandemic, including social stories, visual schedules, expert tips and coping strategies for autism families throughout quarantine.
The BioMed Alliance COVID-19 Information Page
The BioMed Alliance launched a new page providing an overview of resources on COVID-19. The page contains information on BioMed Alliance activities and highlights materials that medical & research societies and relevant authorities have published on the COVID-19 virus. A series of links to relevant information pages is available on the page as well, including useful information on research funding, statistics and links to initiatives such as the European COVID-19 Data Portal. The BioMed Alliance Information page is regularly updated and can be found here.
The General Secretariat of the Council has published a page that gives an overview on the latest meetings, press releases and policies of the Council of the EU and the European Council in relation to the COVID-19 coronavirus outbreak.
Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported. The aim of this study was to perform a review to describe neurological manifestations in patients with COVID -19 and possible neuro-invasive mechanisms of Sars-CoV-2.
COVID-19 Knowledge space
SARS-CoV-2 imposes a threat to human beings, to our economy and society. The Fraunhofer Institute for Algorithms and Scientific Computing SCAI aims at rapidly generating a comprehensive COVID-19 pharmacome and to use the COVID-19 Knowledge space to predict new drug candidates and better treatments against COVID-19.
- Neuroinvasion of SARS-CoV-2 in human and mouse brain (JEM – Journal of Experimental Medicine)
Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects multiple organ systems including the central nervous system (CNS). Yet, there is no consensus on the consequences of CNS infections. Here, we used three independent approaches to probe the capacity of SARS-CoV-2 to infect the brain. First, using human brain organoids, we observed clear evidence of infection with accompanying metabolic changes in infected and neighboring neurons. However, no evidence for type I interferon responses was detected. We demonstrate that neuronal infection can be prevented by blocking ACE2 with antibodies or by administering cerebrospinal fluid from a COVID-19 patient. Second, using mice overexpressing human ACE2, we demonstrate SARS-CoV-2 neuroinvasion in vivo. Finally, in autopsies from patients who died of COVID-19, we detect SARS-CoV-2 in cortical neurons and note pathological features associated with infection with minimal immune cell infiltrates. These results provide evidence for the neuroinvasive capacity of SARS-CoV-2 and an unexpected consequence of direct infection of neurons by SARS-CoV-2.